Hamim Zahir Selected Research

Giant Cell Tumor of Tendon Sheath

11/2021	Exposure-response analysis of efficacy and safety for pexidartinib in patients with tenosynovial giant cell tumor.
1/2021	Evaluation of Potential Drug-Drug Interaction Risk of Pexidartinib With Substrates of Cytochrome P450 and P-Glycoprotein.
1/2021	Population Pharmacokinetic Analysis of Pexidartinib in Healthy Subjects and Patients With Tenosynovial Giant Cell Tumor or Other Solid Tumors.

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Hamim Zahir Research Topics

Disease

4	Neoplasms (Cancer) 01/2021 - 11/2012
3	Giant Cell Tumor of Tendon Sheath 11/2021 - 01/2021
3	Neuralgia (Stump Neuralgia) 01/2019 - 10/2018
3	Venous Thromboembolism 09/2016 - 07/2012
3	Atrial Fibrillation 09/2016 - 10/2013
3	Stroke (Strokes) 09/2016 - 10/2013
2	Headache (Headaches) 10/2018 - 01/2018
2	Sleepiness 10/2018 - 01/2018
2	Hemorrhage 09/2016 - 01/2015
2	Multiple Sclerosis 07/2012 - 05/2012
2	Myocardial Ischemia (Ischemic Heart Diseases) 12/2006 - 10/2006
2	Hypertriglyceridemia 12/2006 - 10/2006
1	Body Weight (Weight, Body) 01/2021
1	Dyspepsia (Indigestion) 10/2018
1	Type 2 Diabetes Mellitus (MODY) 10/2018
1	Dizziness (Lightheadedness) 10/2018
1	Ataxia (Dyssynergia) 01/2018
1	Nausea 01/2018
1	Vertigo (Positional Vertigo) 01/2018
1	Embolism (Embolus) 10/2013
1	Pneumonia (Pneumonitis) 08/2013
1	Germ Cell and Embryonal Neoplasms (Germ Cell Tumor) 08/2013
1	Syncope (Fainting) 08/2013
1	Myxoid Liposarcoma 11/2012
1	Edema (Dropsy) 11/2012
1	Disease Progression 11/2012
1	Bradycardia 07/2012
1	Short Bowel Syndrome 11/2008
1	Gastrointestinal Diseases (Functional Gastrointestinal Disorders) 11/2008
1	Crohn Disease (Crohn's Disease) 11/2008
1	Pain (Aches) 11/2008
1	Diabetes Mellitus 08/2007
1	Hypoalbuminemia 08/2005
1	Anemia 08/2005

Drug/Important Bio-Agent (IBA)

5	mirogabalinIBA 01/2019 - 01/2018
3	pexidartinibIBA 11/2021 - 01/2021
3	LigandsIBA 01/2019 - 10/2018
3	edoxabanIBA 01/2015 - 07/2012
2	Calcium Channels (Calcium Channel)IBA 01/2019 - 10/2018
2	ARQ 197IBA 01/2018 - 08/2013
2	Factor Xa InhibitorsIBA 01/2015 - 10/2013
2	CS 0777IBA 07/2012 - 05/2012
2	Tacrolimus (Prograf)FDA LinkGeneric 08/2007 - 08/2005
2	Sirolimus (Rapamycin)FDA Link 12/2006 - 10/2006
2	Cyclosporine (Ciclosporin)FDA LinkGeneric 12/2006 - 10/2006
1	Phosphotransferases (Kinase)IBA 01/2021
1	EnzymesIBA 10/2018
1	Metformin (Glucophage)FDA LinkGeneric 10/2018
1	Warfarin (Coumadin)FDA LinkGeneric 01/2018
1	Digoxin (Digitek)FDA LinkGeneric 01/2018
1	Cytochrome P-450 CYP2C9IBA 01/2018
1	Caffeine (No Doz)FDA LinkGeneric 01/2018
1	Cytochrome P-450 CYP3AIBA 01/2018
1	Lorazepam (Ativan)FDA LinkGeneric 01/2018
1	Cytochrome P-450 CYP2C19IBA 01/2018
1	Midazolam (Versed)FDA LinkGeneric 01/2018
1	Member 1 Subfamily B ATP Binding Cassette TransporterIBA 01/2018
1	Omeprazole (Prilosec)FDA LinkGeneric 01/2018
1	Cytochrome P-450 CYP1A2 (CYP1A2)IBA 01/2018
1	Ethanol (Ethyl Alcohol)IBA 01/2018
1	Zolpidem (Ambien)FDA LinkGeneric 01/2018
1	Tramadol (K315)FDA LinkGeneric 01/2018
1	prothrombin complex concentrates (PPSB)IBA 09/2016
1	AnticoagulantsIBA 09/2016
1	Vitamin K FDA Link 09/2016
1	N(4)-oleylcytosine arabinosideIBA 09/2016
1	Prothrombin (Factor II)IBA 01/2015
1	Biomarkers (Surrogate Marker)IBA 01/2015
1	Thrombin FDA Link 01/2015
1	Pharmaceutical PreparationsIBA 08/2013
1	PPAR-gamma AgonistsIBA 11/2012
1	efatutazoneIBA 11/2012
1	DiureticsIBA 11/2012
1	AdiponectinIBA 11/2012
1	Transaminases (Aminotransferases)IBA 07/2012
1	Enoxaparin (Lovenox)FDA LinkGeneric 07/2012
1	Sphingosine-1-Phosphate ReceptorsIBA 07/2012
1	sphingosine 1-phosphate (sphingosine-1-phosphate)IBA 05/2012
1	Glucagon (Glukagon)FDA Link 11/2008
1	teduglutideIBA 11/2008
1	Diltiazem (Cardizem)FDA LinkGeneric 08/2005
1	Fluconazole (Zonal)FDA LinkGeneric 08/2005

Therapy/Procedure

1	Anticoagulation Reversal 09/2016
1	Intravenous Administration 01/2015
1	Secondary Prevention 01/2015
1	Therapeutics 11/2012
1	Liver Transplantation 08/2005